NLRP2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for NLRP2 抗体 (C-Term) (ABIN6990400)
抗原
See all NLRP2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- NALP2 Antibody is immunoaffinity chromatography purified IgG.
-
免疫原
- NALP2 antibody was raised against a peptide corresponding to 12 amino acids near the carboxy terminus of human NALP2. The immunogen is located within the last 50 amino acids of NALP2.
-
亚型
- IgG
-
-
-
-
应用备注
-
NALP2 antibody can be used for detection of NALP2 by Western blot at 1 to 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- NALP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- NALP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))
-
别名
- NALP2
-
背景
- NALP2 Antibody: NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1β,-processing activity and is thought to function as a modulator of NF-κ,B and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.
-
基因ID
- 55655
-
NCBI登录号
- NP_060322
-
UniProt
- Q9NX02
-
途径
- Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
-