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NLRP2 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects NLRP2 in WB 和 ELISA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6990400
发货至: 中国
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Quick Overview for NLRP2 抗体 (C-Term) (ABIN6990400)

抗原

See all NLRP2 抗体
NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

适用

  • 33
  • 8
  • 4
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 26
  • 5
  • 2
  • 1

克隆类型

  • 30
  • 4
多克隆

标记

  • 34
This NLRP2 antibody is un-conjugated

应用范围

  • 31
  • 11
  • 8
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    NALP2 Antibody is immunoaffinity chromatography purified IgG.

    免疫原

    NALP2 antibody was raised against a peptide corresponding to 12 amino acids near the carboxy terminus of human NALP2. The immunogen is located within the last 50 amino acids of NALP2.

    亚型

    IgG
  • 应用备注

    NALP2 antibody can be used for detection of NALP2 by Western blot at 1 to 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NALP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    NALP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

    别名

    NALP2

    背景

    NALP2 Antibody: NALP2 belongs to a family of cytoplasmic proteins that have been implicated in cell responses to apoptotic and inflammatory stimuli. Unlike the prototypical NALP protein NALP1, NALP2 only contains a NACHT domain, leucine rich repeat (LRR), and pyrin-containing domain (PYD). This protein interacts with the adapter protein ASC in addition to CARD8 and caspase-1 to form an inflammasome with high proIL-1β,-processing activity and is thought to function as a modulator of NF-κ,B and procaspase-1 activation in macrophages. It has also been suggested that NALP2, in addition to other NALP family members, can act as innate sensors of pathogens in a manner similar to the toll-like receptors (TLRs). At least two alternatively spliced transcript variants encoding distinct isoforms have been found for NALP2.

    基因ID

    55655

    NCBI登录号

    NP_060322

    UniProt

    Q9NX02

    途径

    Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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