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ILP-2 抗体 (N-Term)

BIRC8 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990397
发货至: 中国
  • 抗原 See all ILP-2 (BIRC8) 抗体
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    抗原表位
    • 15
    • 5
    • 4
    N-Term
    适用
    人, 大鼠, 小鼠
    宿主
    • 31
    • 2
    克隆类型
    • 33
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ILP-2 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 10
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
    纯化方法
    ILP-2 Antibody is affinity chromatography purified via peptide column.
    免疫原
    ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2. The immunogen is located within the first 50 amino acids of ILP-2.
    亚型
    IgG
    Top Product
    Discover our top product BIRC8 Primary Antibody
  • 应用备注
    ILP-2 antibody can be used for detection of ILP-2 by Western blot at 1 μ,g/mL. A band at approximately 33 kDa can be detected. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ILP-2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    ILP-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
    别名
    ILP-2 (BIRC8 产品)
    别名
    ILP-2 antibody, ILP2 antibody, hILP2 antibody, baculoviral IAP repeat containing 8 antibody, BIRC8 antibody
    背景
    ILP-2 Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.
    分子量
    33 kDa
    基因ID
    112401
    NCBI登录号
    NP_203127
    UniProt
    Q96P09
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