MAP1 抗体
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北京 101111
Quick Overview for MAP1 抗体 (ABIN6990393)
抗原
See all MAP1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- MAP1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- MAP-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human MAP-1. The immunogen is located within the last 50 amino acids of MAP1.
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亚型
- IgG
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anti-Mannosidase Processing 1 (MAP1) antibody
MAP1 适用: 大鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal MP-1 unconjugated
anti-Mannosidase Processing 1 (MAP1) antibody (Magnetic Particles)MAP1 适用: 大鼠 IP 宿主: 小鼠 Monoclonal MP-1 Magnetic Particles
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应用备注
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MAP1 antibody can be used for the detection of MAP-1 by Western blot at 1 to 4 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MAP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MAP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MAP1 (Mannosidase Processing 1 (MAP1))
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别名
- MAP1
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背景
- MAP1 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Members of the Bcl-2 family are known to be critical regulators of this process. These proteins are characterized by the presence of several conserved motifs termed Bcl-2 homology (BH) domains. A related protein termed MAP-1 has recently been identified. This protein contains a BH3-like domain and induces caspase-dependent apoptosis in mammalian cells when overexpressed. It forms homodimers and associates with Bcl-2 family members such as Bax, Bcl-2, and Bcl-XL in vitro and in vivo. It has been suggested that MAP-1 associates with the tumor suppressor RASSF1A following death receptor activation, allowing a conformational change in Bax that leads to cellular apoptosis.
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基因ID
- 64112
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NCBI登录号
- NP_071434
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UniProt
- Q96BY2
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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