IL22R 抗体 (N-Term)
The 兔 多克隆 anti-IL22R antibody is suitable to detect IL22R in samples from 人 和 大鼠. It has been validated for WB, ELISA, ICC, IF 和 IHC (p).
产品编号 ABIN6990383
发货至:
中国
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Quick Overview for IL22R 抗体 (N-Term) (ABIN6990383)
抗原
IL22R
(Interleukin 22 Receptor (IL22R))
适用
人, 大鼠
宿主
兔
克隆类型
多克隆
标记
This IL22R antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- N-Term
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纯化方法
- IL-22 Receptor Antibody is affinity chromatography purified via peptide column.
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免疫原
- IL-22 receptor antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor. The immunogen is located within the first 50 amino acids of IL-22 Receptor.
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亚型
- IgG
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应用备注
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IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 0.5-1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL and immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples, Immunocytochemistry in human samples and Immunofluorescence in human and rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- IL-22 Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- IL-22 Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- IL22R (Interleukin 22 Receptor (IL22R))
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别名
- IL-22 Receptor
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背景
- IL-22 Receptor Antibody: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
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分子量
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Predicted: 63 kDa
Observed: 65 kDa -
基因ID
- 58985
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NCBI登录号
- NP_067081
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UniProt
- Q8N6P7
抗原
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