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IL22R 抗体 (C-Term)

This anti-IL22R antibody is a 兔 多克隆 antibody detecting IL22R in WB 和 ELISA. Suitable for 人 和 大鼠.
产品编号 ABIN6990379
发货至: 中国

Quick Overview for IL22R 抗体 (C-Term) (ABIN6990379)

抗原

IL22R (Interleukin 22 Receptor (IL22R))

适用

  • 7
  • 2
  • 2
人, 大鼠

宿主

  • 8
  • 1

克隆类型

  • 9
多克隆

标记

  • 7
  • 2
This IL22R antibody is un-conjugated

应用范围

  • 8
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 3
    • 3
    • 2
    • 1
    • 1
    C-Term

    纯化方法

    IL-22 Receptor Antibody is affinity chromatography purified via peptide column.

    免疫原

    IL-22 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human IL-22. The immunogen is located within the last 50 amino acids of IL-22 Receptor.

    亚型

    IgG
  • 应用备注

    IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 1 μ,g/mL. An approximately 62 kDa band can be detected.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    IL-22 Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    IL-22 Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    IL22R (Interleukin 22 Receptor (IL22R))

    别名

    IL-22 Receptor

    背景

    IL-22 Receptor Antibody: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.

    分子量

    62 kDa

    基因ID

    58985

    UniProt

    Q8N6P7
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