MTBP 抗体 (AA 110-160)
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北京 101111
Quick Overview for MTBP 抗体 (AA 110-160) (ABIN6990370)
抗原
See all MTBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 110-160
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纯化方法
- MTBP Antibody is affinity chromatography purified via peptide column.
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免疫原
- MTBP antibody was raised against a 18 amino acid peptide near the center of human MTBP. The immunogen is located within amino acids 110 - 160 of MTBP.
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亚型
- IgG
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anti-MDM2 Binding Protein (MTBP) (AA 853-881), (C-Term) antibody
MTBP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20020 unconjugated
anti-MDM2 Binding Protein (MTBP) antibodyMTBP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 567-724) antibodyMTBP 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 23-350) antibodyMTBP 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 122-139) antibodyMTBP 适用: 人 WB, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-MDM2 Binding Protein (MTBP) (AA 122-139), (Middle Region) antibodyMTBP 适用: 人 WB, EIA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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MTBP antibody can be used for detection of MTBP by Western blot at 1 to 2 μ,g/mL. A 104 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- MTBP Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- MTBP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- MTBP (MDM2 Binding Protein (MTBP))
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别名
- MTBP
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背景
- MTBP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2 and MTBP, were recently discovered. The transcriptional activity of p53 is modulated by posttranslational regulations of the p53 protein including stabilization and acetylation. P53 transcriptionally activates MDM2 gene then the translated MDM2 protein binds to p53 and promotes the degradation of p53 leading to lowering the concentration of p53 protein. MDM2 inhibits both p53 mediated G1 arrest and apoptosis. A recently discovered protein termed MTBP was found to bind to MDM2 and to inhibit the modulation effect of MDM2 on p53. MTBP is expressed in a variety of normal tissues.
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分子量
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Predicted: 104 kDa
Observed: 104 kDa -
基因ID
- 27085
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NCBI登录号
- NP_071328
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UniProt
- Q96DY7
抗原
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