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AVEN 抗体 (C-Term)

AVEN 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990365
发货至: 中国
  • 抗原 See all AVEN 抗体
    AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
    抗原表位
    • 15
    • 13
    • 8
    • 5
    • 1
    • 1
    • 1
    C-Term
    适用
    • 47
    • 12
    • 5
    • 3
    人, 小鼠, 大鼠
    宿主
    • 45
    • 2
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This AVEN antibody is un-conjugated
    应用范围
    • 40
    • 21
    • 13
    • 13
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Aven Antibody is affinity chromatography purified via peptide column.
    免疫原
    Aven antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Aven. The immunogen is located within the last 50 amino acids of Aven.
    亚型
    IgG
    Top Product
    Discover our top product AVEN Primary Antibody
  • 应用备注
    Aven antibody can be used for detection of Aven by Western blot at 1 μ,g/mL. Despite its predicted molecular weight, Aven often migrates at 55 kDa in SDS-PAGE. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Aven Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Aven antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
    别名
    Aven (AVEN 产品)
    别名
    AVEN antibody, pdcd12 antibody, aven antibody, wu:fc08c09 antibody, si:ch211-150c22.4 antibody, PDCD12 antibody, 1700013A01Rik antibody, 1700056A21Rik antibody, mAven-L antibody, mAven-S antibody, apoptosis and caspase activation inhibitor antibody, apoptosis, caspase activation inhibitor L homeolog antibody, apoptosis, caspase activation inhibitor antibody, Aven antibody, AVEN antibody, aven.L antibody, aven antibody
    背景
    Aven Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Aven is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that Aven functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that Aven impedes Apaf-1-mediated caspase activation. Higher levels of Aven mRNA are seen in patients with acute leukemia than in control patients, suggesting that Aven may be useful as a prognostic indicator in leukemia patients.
    基因ID
    57099
    NCBI登录号
    NP_065104
    UniProt
    Q9NQS1
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