TNP1 抗体 (N-Term)
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- 抗原 See all TNP1 抗体
- TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- TP1 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- TP1 antibody was raised against a 20 amino acid synthetic peptide from near the amino terminus of human TP1. The immunogen is located within the first 50 amino acids of TP1.
- 亚型
- IgG
- Top Product
- Discover our top product TNP1 Primary Antibody
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anti-Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) (AA 3-53) antibody
TNP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) (AA 1-55) antibodyTNP1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B5 unconjugated
anti-Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) (AA 12-50) antibodyTNP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transition Protein 1 (During Histone To Protamine Replacement) (TNP1) (C-Term) antibodyTNP1 适用: 人, 小鼠, 大鼠, Pig, 兔, 犬, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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TP1 antibody can be used for detection of TP1 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TP1 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))
- 别名
- TP1 (TNP1 产品)
- 别名
- TNP1 antibody, TP1 antibody, Stp-1 antibody, Tp-1 antibody, STP-1 antibody, TP-1 antibody, transition protein 1 antibody, TNP1 antibody, Tnp1 antibody
- 背景
- TP1 Antibody: Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.
- 分子量
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Predicted: 290 kDa
Observed: 290 kDa - 基因ID
- 7011
- UniProt
- Q99973
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