FAIM 抗体 (C-Term)
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Quick Overview for FAIM 抗体 (C-Term) (ABIN6990345)
抗原
See all FAIM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- FAIM Antibody is affinity chromatography purified via peptide column.
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免疫原
- FAIM antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human FAIM. The immunogen is located within the last 50 amino acids of FAIM.
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亚型
- IgG
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anti-Fas Apoptotic Inhibitory Molecule (FAIM) (AA 1-179) antibody
FAIM 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (Internal Region) antibodyVerified FAIM 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (Internal Region) antibodyFAIM 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (AA 35-84) antibodyFAIM 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 兔, Pig, 猴, 非洲爪蟾, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (AA 143-192) antibodyFAIM 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, Pig, 豚鼠, 猴, 非洲爪蟾, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (N-Term) antibodyFAIM 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (Middle Region) antibodyFAIM 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 兔, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule (FAIM) (N-Term) antibodyFAIM 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, Cow, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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FAIM antibody can be used for detection of FAIM by Western blot at 5 - 10 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- FAIM Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- FAIM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FAIM (Fas Apoptotic Inhibitory Molecule (FAIM))
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别名
- FAIM
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背景
- FAIM Antibody: The susceptibility of primary splenic B cells to Fas-mediated apoptosis is regulated in a receptor-specific fashion. Terminal effectors of B cell Fas-resistance include the known anti-apoptotic proteins Bcl-xL, FLIP, and a recently identified protein termed FAIM. This molecule is broadly expressed in various tissues and exists in at least three isoforms. It is thought that resistance to Fas killing via increased expression of FAIM protects foreign antigen-specific B cells during interactions with FasL-bearing T cells whereas autoreactive B cells are deleted via Fas-dependent cytotoxicity. More recent results have indicated that FAIM interacts with both Trk and p75 neurotrophin receptor and may play a role in promoting neurite outgrowth in different neuronal systems by a mechanism involving the activation of NF-κ,B and the Ras-ERK pathway.
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基因ID
- 55179
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NCBI登录号
- NP_060617
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UniProt
- Q9NVQ4
抗原
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