FAIM3 抗体 (C-Term)
Quick Overview for FAIM3 抗体 (C-Term) (ABIN6990337)
抗原
See all FAIM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Toso Antibody is affinity chromatography purified via peptide column.
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免疫原
- Toso antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human Toso. The immunogen is located within the first 50 amino acids of Toso.
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亚型
- IgG
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anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 1-390) antibody
FAIM3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 124-223) antibodyFAIM3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 51-150) antibodyFAIM3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 1-390) antibodyFAIM3 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 18-251) antibodyFAIM3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 18-262) antibodyFAIM3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (Internal Region) antibodyFAIM3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 18-251) antibodyFAIM3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Toso antibody can be used for detection of Toso by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Toso Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Toso antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
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别名
- Toso
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背景
- Toso Antibody: Apoptosis is an important process by which normal tissue homeostasis and function are maintained. One of the major signals that regulate this process is mediated by the activation of the Fas receptor by its ligand. This leads to the formation of a Fas-associated death domain (FADD)- containing death-inducing signaling complex and the activation of caspase-8, which in turn activates downstream effector caspases, such as caspase-3 and -7. Recent experiments have shown that overexpression of Toso, a novel regulator of Fas-induced apoptosis in lymphoid cells, in Jurkat cells as well as transgenic mice render these cells resistant to Fas-induced apoptosis but not to TRAIL-induced apoptosis. Furthermore, Toso was found to associate with FADD, suggesting that Toso functions by disrupting the formation of the death-inducing signaling complex.
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分子量
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Predicted: 43 kDa
Observed: 41 kDa -
基因ID
- 9214
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NCBI登录号
- NP_005440
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UniProt
- O60667
抗原
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