SKI 抗体 (N-Term)
Quick Overview for SKI 抗体 (N-Term) (ABIN6990332)
抗原
See all SKI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Ski Antibody is affinity chromatography purified via peptide column.
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免疫原
- Ski antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human Ski. The immunogen is located within the first 50 amino acids of Ski.
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亚型
- IgG
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anti-SKI Proto-Oncogene (SKI) (N-Term) antibody
SKI 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SKI Proto-Oncogene (SKI) antibodySKI 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SKI Proto-Oncogene (SKI) antibodySKI 适用: 人, 小鼠, 大鼠, 小鸡, 非洲爪蟾 WB, IHC, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal G8 unconjugated
anti-SKI Proto-Oncogene (SKI) antibodySKI 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SKI Proto-Oncogene (SKI) (AA 21-54) antibodySKI 适用: 人 WB 宿主: 兔 Polyclonal RB54389 unconjugated
anti-SKI Proto-Oncogene (SKI) (N-Term) antibodySKI 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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SkiP antibody can be used for detection of Ski by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Ski Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Ski antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- SKI (SKI Proto-Oncogene (SKI))
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别名
- Ski
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背景
- Ski Antibody: TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. Ski will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.
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基因ID
- 6497
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UniProt
- P12755
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途径
- Stem Cell Maintenance, Tube Formation, Skeletal Muscle Fiber Development
抗原
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