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RYBP 抗体 (C-Term)

This anti-RYBP antibody is a 兔 多克隆 antibody detecting RYBP in WB, ELISA, IHC (p) 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990321
发货至: 中国

Quick Overview for RYBP 抗体 (C-Term) (ABIN6990321)

抗原

See all RYBP 抗体
RYBP (RING1 and YY1 Binding Protein (RYBP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This RYBP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    纯化方法

    DEDAF Antibody is affinity chromatography purified via peptide column.

    免疫原

    DEDAF antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DEDAF. The immunogen is located within the last 50 amino acids of DEDAF.

    亚型

    IgG
  • 应用备注

    DEDAF can be used for detection of DEDAF by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in human and mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    DEDAF Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    DEDAF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    RYBP (RING1 and YY1 Binding Protein (RYBP))

    别名

    DEDAF

    背景

    DEDAF Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD) death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. Several molecules including caspases and adaptor FADD contain DEDs. A novel protein that interacts with DED of caspase-8 and 10, and FADD was identified recently and designated DEDAF for DED associated factor. DEDAF is identical to the transcriptional repressor RYBP. DEDAF/RYBP is expressed in multiple tissues and cell lines. DEDAF interacts with FADD and augments the formation of CD95/FADD/capase-8 complexes at the cell membrane, and interacts with DED-containing DNA biding protein (DEDD) in the nucleus indicating it is involved in the regulation of both cytoplasmic and nuclear events of apoptosis.

    分子量

    32 kDa

    基因ID

    23429

    UniProt

    Q8N488
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