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Arc 抗体 (N-Term)

This anti-Arc antibody is a 兔 多克隆 antibody detecting Arc in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6990311
发货至: 中国

Quick Overview for Arc 抗体 (N-Term) (ABIN6990311)

抗原

See all Arc 抗体
Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

适用

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  • 2
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  • 2
人, 大鼠, 小鼠

宿主

  • 65
  • 5
  • 1

克隆类型

  • 67
  • 4
多克隆

标记

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  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
This Arc antibody is un-conjugated

应用范围

  • 62
  • 22
  • 21
  • 14
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  • 8
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 10
    • 5
    • 5
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    • 2
    • 2
    • 2
    • 1
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    N-Term

    纯化方法

    ARC Antibody is affinity chromatography purified via peptide column.

    免疫原

    ARC antibody was raised against a 17 amino acid peptide near the amino terminus of human ARC. The immunogen is located within the first 50 amino acids of ARC.

    亚型

    IgG
  • 应用备注

    ARC antibody can be used for detection of ARC by Western blot at 1:500 dilution. An approximately 25 kDa band can be detected.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ARC Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ARC antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

    别名

    ARC

    背景

    ARC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.

    分子量

    25 kDa

    基因ID

    8996

    NCBI登录号

    NP_003937

    UniProt

    O60936
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