BCL10 抗体 (N-Term)
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北京 101111
Quick Overview for BCL10 抗体 (N-Term) (ABIN6990308)
抗原
See all BCL10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Bcl-10 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Bcl10 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human Bcl10. The immunogen is located within the first 50 amino acids of Bcl-10.
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亚型
- IgG
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anti-B-Cell CLL/lymphoma 10 (BCL10) antibody
KD Validated BCL10 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 23GB1410 unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 小鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 4F8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyKD Validated BCL10 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB2925 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal BL10-411 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 122-168) antibodyBCL10 适用: 人 IHC, IF, FACS, StM 宿主: 兔 Monoclonal BL10-2988R unconjugated Recombinant Antibody
anti-B-Cell CLL/lymphoma 10 (BCL10) antibodyBCL10 适用: 人, 犬 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 6A8 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 98-234) antibodyBCL10 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3C11F4 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-143) antibodyBCL10 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1185CT13-2-1-2 unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) antibodyBCL10 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 10 (BCL10) (AA 1-233) antibodyBCL10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Bcl-10 antibody can be used for detection of BCL10 by Western blot at 0.5 μ,g/mL. dilution. An approximately 31 kDa band can be detected. Antibody can also be used for immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Bcl-10 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- Bcl-10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BCL10 (B-Cell CLL/lymphoma 10 (BCL10))
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别名
- Bcl-10
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背景
- Bcl-10 Antibody: Apoptosis is related to many diseases including cancer. Cell death signals are transduced by death domain (DD) and caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include ARC, RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD containing protein was recently identified by several groups and designated Bcl10, CIPER, mE10, CARMEN, CLAP. Bcl10 is a cellular homolog of the equine herpesvirus-2 E-10 gene. Overexpression of Bcl10 induces JNK, p38, and NF-κ,B activation. Bcl10 interacts with caspase-9 and enhances pro-caspase-9 processing and induces apoptosis through caspase-9 activation. Bcl10 exhibits a variety of mutations in MALT lymphomas and in B and T cell lineage lymphomas indicating that it may be commonly involved in the pathogenesis of human malignancy. Bcl10 is expressed in many human and murine tissues and cell lines.
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分子量
- 31 kDa
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基因ID
- 8915
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UniProt
- O95999
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins
抗原
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