HAVCR1 抗体 (AA 230-280)
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北京 101111
Quick Overview for HAVCR1 抗体 (AA 230-280) (ABIN6990296)
抗原
See all HAVCR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 230-280
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纯化方法
- TIM-1 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-TIM-1 antibody was raised against a peptide corresponding to 16 amino acids near the center terminus of human TIM-1. The immunogen is located within amino acids 230 - 280 of TIM-1.
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亚型
- IgG
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应用备注
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WB: 1-8 μ,g/mL
Antibody validated: Western Blot in human samples. All other applications and species not yet tested -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TIM-1 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TIM-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
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别名
- TIM-1
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物质类
- Virus
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背景
- TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.
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分子量
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Predicted: 44kD
Observed: 60kD (Post-modification: 4 N-linked glycosylation) kDa -
基因ID
- 26762
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NCBI登录号
- NP_036338
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UniProt
- Q96D42
抗原
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