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HAVCR1 抗体 (AA 230-280)

This anti-HAVCR1 antibody is a 兔 多克隆 antibody detecting HAVCR1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN6990296
发货至: 中国

Quick Overview for HAVCR1 抗体 (AA 230-280) (ABIN6990296)

抗原

See all HAVCR1 抗体
HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

适用

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宿主

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克隆类型

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多克隆

标记

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This HAVCR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    AA 230-280

    纯化方法

    TIM-1 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-TIM-1 antibody was raised against a peptide corresponding to 16 amino acids near the center terminus of human TIM-1. The immunogen is located within amino acids 230 - 280 of TIM-1.

    亚型

    IgG
  • 应用备注

    WB: 1-8 μ,g/mL

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TIM-1 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TIM-1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

    别名

    TIM-1

    物质类

    Virus

    背景

    TIM-1 Antibody: The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.

    分子量

    Predicted: 44kD

    Observed: 60kD (Post-modification: 4 N-linked glycosylation) kDa

    基因ID

    26762

    NCBI登录号

    NP_036338

    UniProt

    Q96D42
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