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BCAP31 抗体 (C-Term)

This anti-BCAP31 antibody is a 兔 多克隆 antibody detecting BCAP31 in WB, ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990280
发货至: 中国

Quick Overview for BCAP31 抗体 (C-Term) (ABIN6990280)

抗原

See all BCAP31 抗体
BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This BCAP31 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    纯化方法

    BAP31 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-BAP31 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human BAP31. The immunogen is located within the last 50 amino acids of BAP31.

    亚型

    IgG
  • 应用备注

    WB: 0.5-2 μ,g/mL, IHC: 2 μ,g/mL.

    Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in rat samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    BAP31 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    BAP31 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

    别名

    BAP31

    背景

    BAP31 Antibody: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death.

    分子量

    Predicted: 28kD

    Observed: 28kD kDa

    基因ID

    10134

    NCBI登录号

    NP_005736

    UniProt

    P51572

    途径

    Positive Regulation of Endopeptidase Activity
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