BCAP31 抗体 (C-Term)
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北京 101111
Quick Overview for BCAP31 抗体 (C-Term) (ABIN6990280)
抗原
See all BCAP31 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- BAP31 Antibody is affinity chromatography purified via peptide column.
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免疫原
- Anti-BAP31 antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human BAP31. The immunogen is located within the last 50 amino acids of BAP31.
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亚型
- IgG
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应用备注
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WB: 0.5-2 μ,g/mL, IHC: 2 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry in rat samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- BAP31 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- BAP31 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))
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别名
- BAP31
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背景
- BAP31 Antibody: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death.
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分子量
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Predicted: 28kD
Observed: 28kD kDa -
基因ID
- 10134
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NCBI登录号
- NP_005736
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UniProt
- P51572
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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