DNASE2 抗体 (C-Term)
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Quick Overview for DNASE2 抗体 (C-Term) (ABIN6990276)
抗原
See all DNASE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- DNase II Antibody is affinity chromatography purified via peptide column.
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免疫原
- DNase II antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DNase II. The immunogen is located within the last 50 amino acids of DNase II.
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亚型
- IgG
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anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 25-90) antibody
DNASE2 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 19-360) antibodyDNASE2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 19-152) antibodyDNASE2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 261-360) antibodyDNASE2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 1-360) antibodyDNASE2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 1-360) antibodyDNASE2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Deoxyribonuclease II, Lysosomal (DNASE2) (AA 347-360) antibodyDNASE2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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DNase II antibody can be used for detection of DNase II expression by Western blot at 0.5 μ,g/mL. An approximate 40 kDa band can be detected, which represents the pro-enzyme of DNase II. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- DNase II Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- DNase II antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))
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别名
- DNase II
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背景
- DNase II Antibody: Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation. These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins including AIF and Acinus. DNase II causes both chromatin condensation and DNA fragmentation. The genes encoding human, porcine, and murine DNase II have been cloned. The DNase II gene encodes a 40 kDa proenzyme. The mature enzyme consists of two non-identical subunits, the 32 kDa (alpha) and 12 kDa (beta) chains, generated by proteolytic processing. Overexpression of DNase II induces chromatin condensation. DNase II is ubiquitously expressed in human tissues.
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分子量
- Aprox: 40 kDa
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基因ID
- 1777
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UniProt
- O00115
抗原
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