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ORAI1 抗体 (C-Term)

ORAI1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F6H5 unconjugated
产品编号 ABIN6990200
发货至: 中国
  • 抗原 See all ORAI1 抗体
    ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
    抗原表位
    • 11
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 61
    • 24
    • 11
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 58
    • 5
    • 1
    小鼠
    克隆类型
    • 59
    • 5
    单克隆
    标记
    • 29
    • 8
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ORAI1 antibody is un-conjugated
    应用范围
    • 50
    • 37
    • 18
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    ORAI1 antibody is predicted to have no cross reactivity to other members in the ORAI family.
    纯化方法
    ORAI1 Monoclonal Antibody is Protein A purified.
    免疫原
    Mouse monoclonal ORAI1 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human ORAI1.
    克隆位点
    3F6H5
    亚型
    IgG1
    Top Product
    Discover our top product ORAI1 Primary Antibody
  • 应用备注
    ORAI1 antibody can be used for detection of ORAI1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ORAI1 Monoclonal Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    ORAI1 monoclonal antibody can be stored at -20°C, stable for one year.
  • 抗原
    ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
    别名
    ORAI1 (ORAI1 产品)
    别名
    CRACM1 antibody, ORAT1 antibody, TMEM142A antibody, RGD1311873 antibody, D730049H07Rik antibody, Tmem142a antibody, orai-1 antibody, im:7146264 antibody, orai1 antibody, tmem142a antibody, zgc:109721 antibody, orai2 antibody, ORAI1 antibody, LOC100218031 antibody, ORAI calcium release-activated calcium modulator 1 antibody, ORAI calcium release-activated calcium modulator 1b antibody, ORAI calcium release-activated calcium modulator 1 S homeolog antibody, ORAI1 antibody, Orai1 antibody, orai1b antibody, orai1.S antibody, orai1 antibody
    背景
    ORAI1 Monoclonal Antibody: Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI1 is a recently identified four-transmembrane spanning protein that is an essential component of CRAC. A missense mutation in this protein in humans is the cause of one fo rm of hereditary severe combined immune deficiency (SCID) which results in ablated T-cell Ca++ entry. It has been suggested that ORAI1 functions as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor. ORAI1 often migrates at a higher than expected molecular weight in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ORAI2 or ORAI3.
    分子量
    Predicted: 33 kDa

    Observed: 56 kDa
    基因ID
    84876
    UniProt
    Q96D31
    途径
    TCR Signaling, BCR Signaling
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