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SARS-CoV-2 NSP14 抗体 (AA 120-170)

This anti-SARS-CoV-2 NSP14 antibody is a 兔 多克隆 antibody detecting SARS-CoV-2 NSP14 in ELISA 和 IHC. Suitable for SARS Coronavirus-2 (SARS-CoV-2).
产品编号 ABIN6990150
发货至: 中国
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Quick Overview for SARS-CoV-2 NSP14 抗体 (AA 120-170) (ABIN6990150)

抗原

SARS-CoV-2 NSP14 (ExoN) (SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14) (ExoN))

适用

SARS Coronavirus-2 (SARS-CoV-2)

宿主

  • 1
  • 1

克隆类型

  • 2
多克隆

标记

  • 2
This SARS-CoV-2 NSP14 antibody is un-conjugated

应用范围

ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 1
    • 1
    AA 120-170

    纯化方法

    SARS-CoV-2 (COVID-19) NSP14 (ExoN) Antibody is affinity chromatography purified via peptide column.

    免疫原

    Anti-SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody was raised against a peptide corresponding to 14 amino acids near the center of SARS-CoV-2 (COVID-19) NSP14 (ExoN) protein. The immunogen is located between 120-170 amino acids of SARS-CoV-2 (COVID-19) NSP14 (ExoN).

    亚型

    IgG
  • 应用备注

    IHC: 0.5 μ,g/mL .

    Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody can detect 2 ng of free peptide at 1 μ,g/mL in ELISA. All other applications and species not yet tested

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    SARS-CoV-2 (COVID-19) NSP14 (ExoN) Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    SARS-CoV-2 (COVID-19) NSP14 (ExoN) antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    SARS-CoV-2 NSP14 (ExoN) (SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14) (ExoN))

    别名

    SARS-CoV-2 Guanine-N7 Methyltransferase (NSP14)

    物质类

    Viral Protein

    背景

    Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019-20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP14 (ExoN) is an enzyme possessing two different activities: an exoribonuclease activity acting on both ssRNA and dsRNA in a 3' to 5' direction and a N7-guanine methyltransferase activity (3,4,5). It acts as a proofreading exoribonuclease for RNA replication, thereby lowering The sensitivity of the virus to RNA mutagens(6,7,8).

    基因ID

    43740578

    NCBI登录号

    YP_009725309

    UniProt

    P0DTC1
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