SARS-CoV-2 Spike 抗体
Quick Overview for SARS-CoV-2 Spike 抗体 (ABIN6990096)
抗原
See all SARS-CoV-2 Spike 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Antibody recognizes 2019-nCoV S-RBD Protein.
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纯度
- 95,00%
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免疫原
- Cultured in vitro under conditions free from animal derived components.
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亚型
- IgG1
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应用备注
- Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 5.0 mg/mL
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缓冲液
- PBS, pH 7.4
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储存条件
- -20 °C,4 °C
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储存方法
- 24 months from manufacturing at <-20 °C, 1 month, 2 to 8 °C under sterile conditions.
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- SARS-CoV-2 Spike
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物质类
- Viral Protein
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背景
- The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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基因ID
- 43740568
抗原
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