电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

INPP5D 抗体 (pTyr1020)

INPP5D 适用: 人 WB, IP, IF (cc) 宿主: 兔 Monoclonal 1H11 unconjugated
产品编号 ABIN6989964
发货至: 中国
  • 抗原 See all INPP5D 抗体
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    抗原表位
    • 18
    • 18
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr1020
    适用
    • 81
    • 57
    • 36
    • 20
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 80
    • 2
    克隆类型
    • 70
    • 12
    单克隆
    标记
    • 31
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This INPP5D antibody is un-conjugated
    应用范围
    • 58
    • 19
    • 16
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Synthetic phospho-Peptide corresponding to residues surrounding Tyr1020 of human SHIP.
    克隆位点
    1H11
    亚型
    IgG
    Top Product
    Discover our top product INPP5D Primary Antibody
  • 应用备注
    WB 1:300-5000
    IF(ICC) 1:50-200
    IP(1-2 μg)
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
    别名
    SHIP (INPP5D 产品)
    别名
    INPP5D antibody, 256.t00004 antibody, 13.t00027 antibody, ship antibody, ship1 antibody, AI323613 antibody, SHIP antibody, SHIP-1 antibody, SHIP1 antibody, s-SHIP antibody, SIP-145 antibody, hp51CN antibody, inositol polyphosphate-5-phosphatase D antibody, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 antibody, inositol polyphosphate 5-phosphatase antibody, inositol polyphosphate-5-phosphatase D L homeolog antibody, INPP5D antibody, LOC100446045 antibody, inpp5d antibody, EHI_159880 antibody, EHI_153490 antibody, inpp5d.L antibody, LOC100380693 antibody, Inpp5d antibody
    背景

    Synonyms: Inositol polyphosphate 5 phosphatase of 145 kDa antibody, 4 antibody, 5-trisphosphate 5-phosphatase 1 antibody, hp51CN antibody, Inositol polyphosphate 5 phosphatase 145 kDa antibody, Inositol polyphosphate 5 phosphatase antibody, Inositol polyphosphate-5-phosphatase of 145 kDa antibody, INPP5D antibody, MGC104855 antibody, MGC142140 antibody, MGC142142 antibody, p150Ship antibody, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 1 antibody, Phosphatidylinositol-3 antibody, SH2 containing inositol phosphatase isoform b antibody, SH2 domain containing inositol 5' phosphatase 1 antibody, SH2 domain containing inositol phosphatase 1 antibody, SH2 domain-containing inositol phosphatase 1 antibody, SH2 domain-containing inositol-5'-phosphatase 1 antibody, SHIP-1 antibody, SHIP1 antibody, SHIP1_HUMAN antibody, Signaling inositol polyphosphate 5 phosphatase SIP 145 antibody, SIP-145 antibody, SIP145 antibody

    Background: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.

    基因ID
    3635
    UniProt
    Q92835
    途径
    TCR Signaling, BCR Signaling, Warburg Effect
You are here:
客服