INPP5D 抗体 (pTyr1020)
Quick Overview for INPP5D 抗体 (pTyr1020) (ABIN6989964)
抗原
See all INPP5D 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr1020
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic phospho-Peptide corresponding to residues surrounding Tyr1020 of human SHIP.
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亚型
- IgG
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anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (AA 959-1188) antibody
INPP5D 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 9G11 unconjugated Recombinant Antibody
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (N-Term) antibodyINPP5D 适用: 人 WB, ICC, ICFC 宿主: 小鼠 Monoclonal SHIP-01 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
IF(ICC) 1:50-200
IP(1-2 μg) -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
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别名
- SHIP
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背景
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Synonyms: Inositol polyphosphate 5 phosphatase of 145 kDa antibody, 4 antibody, 5-trisphosphate 5-phosphatase 1 antibody, hp51CN antibody, Inositol polyphosphate 5 phosphatase 145 kDa antibody, Inositol polyphosphate 5 phosphatase antibody, Inositol polyphosphate-5-phosphatase of 145 kDa antibody, INPP5D antibody, MGC104855 antibody, MGC142140 antibody, MGC142142 antibody, p150Ship antibody, Phosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 1 antibody, Phosphatidylinositol-3 antibody, SH2 containing inositol phosphatase isoform b antibody, SH2 domain containing inositol 5' phosphatase 1 antibody, SH2 domain containing inositol phosphatase 1 antibody, SH2 domain-containing inositol phosphatase 1 antibody, SH2 domain-containing inositol-5'-phosphatase 1 antibody, SHIP-1 antibody, SHIP1 antibody, SHIP1_HUMAN antibody, Signaling inositol polyphosphate 5 phosphatase SIP 145 antibody, SIP-145 antibody, SIP145 antibody
Background: SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
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基因ID
- 3635
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UniProt
- Q92835
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途径
- TCR Signaling, BCR Signaling, Warburg Effect
抗原
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