电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

COMT 抗体

This anti-COMT antibody is a 兔 多克隆 antibody detecting COMT in WB, IHC 和 IF. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6989763
发货至: 中国

Quick Overview for COMT 抗体 (ABIN6989763)

抗原

See all COMT 抗体
COMT (Catechol-O-Methyltransferase (COMT))

适用

  • 60
  • 48
  • 40
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 70
  • 22
  • 3
  • 1

克隆类型

  • 66
  • 30
多克隆

标记

  • 64
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COMT antibody is un-conjugated

应用范围

  • 61
  • 41
  • 29
  • 26
  • 24
  • 13
  • 13
  • 8
  • 8
  • 3
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 42-221 of human COMT (NP_009294.1).

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC()
    IF()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    COMT (Catechol-O-Methyltransferase (COMT))

    别名

    COMT

    背景

    Synonyms: COMT,HEL-S-98n

    Background: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters.

    基因ID

    1312

    UniProt

    P21964

    途径

    Steroid Hormone Biosynthesis, SARS-CoV-2 Protein Interactome
You are here:
Chat with us!