CHCHD2 抗体
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- 抗原 See all CHCHD2 products
- CHCHD2 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 (CHCHD2))
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHCHD2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 75-145 of human CHCHD2 (NP_057223.1).
- 亚型
- IgG
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anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 (CHCHD2) (AA 75-145) antibody
KO Validated CHCHD2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 (CHCHD2) (Internal Region) antibodyCHCHD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 (CHCHD2) (AA 96-130) antibodyCHCHD2 适用: 小鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 (CHCHD2) (AA 74-103) antibodyCHCHD2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB27708 unconjugated
anti-Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 (CHCHD2) (AA 81-111), (Middle Region) antibodyCHCHD2 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
IF(ICC) 1:50-200
IF() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CHCHD2 (Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 2 (CHCHD2))
- 别名
- CHCHD2 (CHCHD2 产品)
- 别名
- AL033347 antibody, Etohi6 antibody, C7orf17 antibody, CHCHD9 antibody, chchd2 antibody, coiled-coil-helix-coiled-coil-helix domain containing 2 antibody, coiled-coil-helix-coiled-coil-helix domain containing 2 L homeolog antibody, Chchd2 antibody, CHCHD2 antibody, chchd2.L antibody
- 背景
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Synonyms: CHCHD2,C7orf17,MNRR1,NS2TP,PARK22
Background: The protein encoded by this gene belongs to a class of eukaryotic CX(9)C proteins characterized by four cysteine residues spaced ten amino acids apart from one another. These residues form disulfide linkages that define a CHCH fold. In response to stress, the protein translocates from the mitochondrial intermembrane space to the nucleus where it binds to a highly conserved 13 nucleotide oxygen responsive element in the promoter of cytochrome oxidase 4I2, a subunit of the terminal enzyme of the electron transport chain. In concert with recombination signal sequence-binding protein J, binding of this protein activates the oxygen responsive element at four percent oxygen. In addition, it has been shown that this protein is a negative regulator of mitochondria-mediated apoptosis. In response to apoptotic stimuli, mitochondrial levels of this protein decrease, allowing BCL2-associated X protein to oligomerize and activate the caspase cascade. Pseudogenes of this gene are found on multiple chromosomes. Alternative splicing results in multiple transcript variants.
- 基因ID
- 51142
- UniProt
- Q9Y6H1
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