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Recombinant Cyclin E2 抗体 (C-Term)

The 兔 单克隆 anti-Cyclin E2 antibody is suitable to detect Cyclin E2 in samples from 人. It has been validated for WB, FACS, IHC (p), IF (cc), IHC (fro) 和 IF (p).
产品编号 ABIN6989714
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Recombinant Cyclin E2 抗体 (C-Term) (ABIN6989714)

抗原

See all Cyclin E2 (CCNE2) 抗体
Cyclin E2 (CCNE2)

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This Cyclin E2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    C-Term

    原理

    Cyclin E2 Recombinant Antibody

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human Cyclin E2 protein, around C-terminal 100aa.

    亚型

    IgG
  • 应用备注

    WB(WB(1:500-2000)), FCM(FCM(1:50-100)), IHC-P(IHC-P(1:50-200)), IHC-F(IHC-F(1:50-200)), IF(IHC-P)(IF(IHC-P)(1:50-200)), IF(ICC)(IF(ICC)(1:50-200))

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Cyclin E2 (CCNE2)

    别名

    Cyclin E2

    背景

    Synonyms: Cyclin E2 phospho T392, p-Cyclin E2 phospho T392,CCN E2, CCNE 2, CCNE2, CCNE2 protein, CYC E2, CYCE 2, CYCE2, CyclinE2, G1/S-specic cyclin E2, G1/S-specic cyclin E2.

    Background: The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers. Unlike Cyclin E1, which is expressed in great majority of proliferating normal and neoplastically transformed cells, Cyclin E2 levels are low to undetectable in non transformed cells and increase significantly in neoplasm derived cells.

    基因ID

    9134

    UniProt

    O96020

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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