BAT3 抗体
Quick Overview for BAT3 抗体 (ABIN6989697)
抗原
See all BAT3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic Peptide within C-terminal Human BAT3.
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亚型
- IgG
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anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibody
BAT3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-1126) antibodyBAT3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig, 猴, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 943-992) antibodyBAT3 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibodyBAT3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (Internal Region) antibodyVerified BAT3 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (AA 1-200) antibodyBAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Large Proline-Rich Protein BAT3 (BAT3) (C-Term) antibodyBAT3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- BAT3 (Large Proline-Rich Protein BAT3 (BAT3))
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别名
- BAT3
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背景
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Synonyms: 2410045D21Rik antibody, AA408914 antibody, BAG 6 antibody, BAG family molecular chaperone regulator 6 antibody, BAG-6 antibody, BAG6 antibody, BAG6_HUMAN antibody, BAT 3 antibody, BAT3 antibody, BCL2-associated athanogene 6 antibody, D17H6S52E antibody, D6S52E antibody, G3 antibody, HLA B associated transcript 3 antibody, HLA-B associated transcript 3 antibody, HLA-B associated transcript-3 antibody, HLA-B-associated transcript 3 antibody, large proline rich protein BAG6 antibody, Large proline rich protein BAT3 antibody, Large proline-rich protein BAG6 antibody, large proline-rich protein BAT3 antibody, Protein G3 antibody, Protein Scythe antibody, Scythe antibody, Scythe, homolog of Xenopus antibody
Background: Chaperone that plays a key role in various processes such as apoptosis, insertion of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane and regulation of chromatin. Acts in part by regulating stability of proteins and their degradation by the proteasome. Participates in endoplasmic reticulum stress-induced apoptosis via its interaction with AIFM1/AIF by regulating AIFM1/AIF stability and preventing its degradation. Also required during spermatogenesis for synaptonemal complex assembly via its interaction with HSPA2, by inhibiting polyubiquitination and subsequent proteasomal degradation of HSPA2. Required for selective ubiquitin-mediated degradation of defective nascent chain polypeptides by the proteasome. In this context, may play a role in immuno-proteasomes to generate antigenic peptides via targeted degradation, thereby playing a role in antigen presentation in immune response. Key component of the BAG6/BAT3 complex, a cytosolic multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. BAG6/BAT3 acts by facilitating TA membrane proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins and transfers them to ASNA1/TRC40 for targeting to the endoplasmic reticulum membrane.
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基因ID
- 7917
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UniProt
- P46379
抗原
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