DBF4 抗体 (N-Term)
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北京 101111
Quick Overview for DBF4 抗体 (N-Term) (ABIN6989658)
抗原
See all DBF4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- DBF4 Monoclonal Antibody
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic Peptide within N-terminal human DBF4.
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亚型
- IgG
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应用备注
- WB(1:300-5000), FCM(1:20-100)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- DBF4 (DBF4 Homolog (DBF4))
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别名
- DBF4
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背景
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Synonyms: Activator of S phase kinase antibody, ASK antibody, CHIF antibody, Chiffon homolog A antibody, DBF4 antibody, DBF4 homolog (S. cerevisiae) antibody, DBF4 homolog antibody, DBF4 type zinc finger containing protein 1 antibody, DBF4 zinc finger A antibody, DBF4 zinc finger antibody, DBF4, S. cerevisiae, homolog of antibody, DBF4-type zinc finger-containing protein 1 antibody, DBF4A antibody, DBF4A_HUMAN antibody, Dumbbell former 4, S. cerevisiae, homolog of antibody, OTTHUMP00000161661 antibody, Protein DBF4 homolog A antibody, ZDBF1 antibody, Zinc finger, DBF-type containing 1 antibody
Background: Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle. Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
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基因ID
- 10926
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UniProt
- Q9UBU7
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途径
- Mitotic G1-G1/S Phases, DNA Replication
抗原
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