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ERAP1 抗体

This anti-ERAP1 antibody is a 兔 单克隆 antibody detecting ERAP1 in WB. Suitable for 人.
产品编号 ABIN6989656
发货至: 中国

Quick Overview for ERAP1 抗体 (ABIN6989656)

抗原

See all ERAP1 抗体
ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

适用

  • 36
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  • 1
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宿主

  • 35
  • 2

克隆类型

  • 32
  • 5
单克隆

标记

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  • 1
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This ERAP1 antibody is un-conjugated

应用范围

  • 23
  • 18
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Western Blotting (WB)

克隆位点

3H62
  • 交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic Peptide corresponding to C-terminal human ERAP1.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

    别名

    ERAP1

    背景

    Synonyms: A LAP antibody, A-LAP antibody, Adipocyte derived leucine aminopeptidase antibody, Adipocyte-derived leucine aminopeptidase antibody, ALAP antibody, Aminopeptidase PILS antibody, Aminopeptidase regulator of TNFR1 shedding antibody, APPILS antibody, ARTS 1 antibody, ARTS-1 antibody, Arts1 antibody, Endoplasmic reticulum aminopeptidase 1 antibody, Endoplasmic reticulum aminopeptidase associated with antigen processing antibody, ERAAP antibody, ERAAP1 antibody, ERAP 1 antibody, Erap1 antibody, ERAP1_HUMAN antibody, KIAA0525 antibody, kiaa0525 protein antibody, PILS AP antibody, PILS-AP antibody, PILSA antibody, PILSAP antibody, Puromycin insensitive leucyl specific aminopeptidase antibody, Puromycin-insensitive leucyl-specific aminopeptidase antibody, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody, type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody, VEGF-induced aminopeptidase antibody

    Background: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

    基因ID

    51752

    UniProt

    Q9NZ08
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