CD16 抗体
Quick Overview for CD16 抗体 (ABIN6989632)
抗原
See all CD16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Synthetic Peptide within C-terminal human CD16.
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- CD16
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别名
- CD16
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背景
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Synonyms: CD 16 antibody, CD 16a antibody, CD16 antibody, CD16a antibody, CD16a antigen antibody, CD16B antibody, CD16b antigen antibody, Fc fragment of IgG antibody, Fc fragment of IgG low affinity IIIa receptor (CD16) antibody, Fc fragment of IgG low affinity IIIa receptor antibody, Fc fragment of IgG receptor IIIa antibody, Fc fragment of IgG, low affinity III, receptor (CD16) antibody, Fc fragment of IgG, low affinity III, receptor for (CD16) antibody
Background: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer(NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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基因ID
- 2214
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UniProt
- P08637
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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