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Thyroglobulin 抗体

This anti-Thyroglobulin antibody is a 兔 单克隆 antibody detecting Thyroglobulin in IHC, WB 和 IHC (p). Suitable for 人.
产品编号 ABIN6989610
发货至: 中国

Quick Overview for Thyroglobulin 抗体 (ABIN6989610)

抗原

See all Thyroglobulin (TG) 抗体
Thyroglobulin (TG)

适用

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宿主

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克隆类型

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单克隆

标记

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This Thyroglobulin antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

2H4
  • 交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant protein within C-terminal human Thyroglobulin.

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Thyroglobulin (TG)

    别名

    Thyroglobulin

    背景

    Synonyms: AITD 3 antibody, AITD3 antibody, hTG antibody, TDH3 antibody, Tg antibody, TGN antibody, THYG_HUMAN antibody, Thyroglobulin antibody

    Background: Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

    基因ID

    7038

    UniProt

    P01266

    途径

    Thyroid Hormone Synthesis
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