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NEK6 抗体 (AA 81-180)

NEK6 适用: 大鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6989319
发货至: 中国
  • 抗原 See all NEK6 抗体
    NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
    抗原表位
    • 14
    • 8
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 81-180
    适用
    • 36
    • 24
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 46
    • 4
    克隆类型
    • 44
    • 6
    多克隆
    标记
    • 19
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEK6 antibody is un-conjugated
    应用范围
    • 23
    • 19
    • 16
    • 12
    • 12
    • 8
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NEK6
    亚型
    IgG
    Top Product
    Discover our top product NEK6 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
    别名
    NEK6 (NEK6 产品)
    别名
    1300007C09Rik antibody, si:ch211-167p9.4 antibody, ATNEK5 antibody, MOE17.17 antibody, NIMA-RELATED KINASE5 antibody, NIMA-related kinase 5 antibody, SID6-1512 antibody, NIMA (never in mitosis gene a)-related expressed kinase 6 antibody, NIMA-related kinase 6 antibody, NIMA related kinase 6 antibody, Serine/Threonine kinase catalytic domain protein antibody, NIMA-related kinase 6 S homeolog antibody, Nek6 antibody, nek6 antibody, NEK6 antibody, NEK5 antibody, nek6.S antibody
    背景

    Synonyms: Highly similar to cell cycle protein kinase CDC5/MSD2, NEK6, NEK6_HUMAN, Never in mitosis A-related kinase 6, NIMA (Never In Mitosis Gene A) Related Kinase 6, NimA related protein kinase 6, NimA-related protein kinase 6, Protein kinase SID6 1512, Protein kinase SID6-1512, Putative serine threonine protein kinase, Serine/threonine protein kinase Nek6, Serine/threonine-protein kinase Nek6, SID61512.

    Background: Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.

    基因ID
    10783
    UniProt
    Q9HC98
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