LSM6 抗体
Quick Overview for LSM6 抗体 (ABIN6989235)
抗原
See all LSM6 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LSM6:31-80/80
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亚型
- IgG
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anti-LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6) (AA 1-80) antibody
LSM6 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 4B5-1B10 unconjugated
anti-LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6) (C-Term) antibodyLSM6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马, 兔, 猴, 非洲爪蟾, Pig, Bat, Hamster, 小鸡, Drosophila melanogaster WB 宿主: 兔 Polyclonal unconjugated
anti-LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6) (N-Term) antibodyLSM6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 斑马鱼, 马, 兔, 猴, 非洲爪蟾, Pig, Bat, Hamster, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6) antibodyLSM6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IHC-P 1:200-400
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- LSM6 (LSM6 Homolog, U6 Small Nuclear RNA Associated (LSM6))
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别名
- LSM6
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背景
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Synonyms: LSM 6, LSM6 homolog U6 small nuclear RNA associated, LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae), Sm protein F, U6 snRNA associated Sm like protein LSm6, YDR378C.
Background: Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2, MIM 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Apr 2004] Function : Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway. Component of the nuclear LSM2-LSM8 complex, which is involved in splicing of nuclear mRNAs. LSM2-LSM8 associates with multiple snRNP complexes containing the U6 snRNA (U4/U6 di-snRNP, spliceosomal U4/U6.U5 tri-snRNP, and free U6 snRNP). It binds directly to the 3'-terminal U-tract of U6 snRNA and plays a role in the biogenesis and stability of the U6 snRNP and U4/U6 snRNP complexes. LSM2-LSM8 probably also is involved degradation of nuclear pre-mRNA by targeting them for decapping, and in processing of pre-tRNAs, pre-rRNAs and U3 snoRNA. Subunit : Component of the heptameric LSM1-LSM7 complex, which consists of LSM1, LSM2, LSM3, LSM4, LSM5, LSM6 and LSM7. Component of the heptameric LSM2-LSM8 complex, which consists of LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. The LSm subunits form a seven-membered ring structure with a doughnut shape. Similarity : Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
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基因ID
- 11157
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UniProt
- P62312
抗原
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