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GIPC1 抗体 (AA 171-270)

This anti-GIPC1 antibody is a 兔 多克隆 antibody detecting GIPC1 in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN6989016
发货至: 中国

Quick Overview for GIPC1 抗体 (AA 171-270) (ABIN6989016)

抗原

See all GIPC1 抗体
GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

适用

  • 51
  • 20
  • 12
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠, 大鼠

宿主

  • 47
  • 4
  • 2
  • 1

克隆类型

  • 53
  • 1
多克隆

标记

  • 28
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GIPC1 antibody is un-conjugated

应用范围

  • 34
  • 25
  • 13
  • 13
  • 9
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 9
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 171-270

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GIPC1?

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

    别名

    GIPC1

    背景

    Synonyms: C19ORF3, Chromosome 19 open reading frame 3, GIPC, GLUT1 C terminal binding protein, GLUT1CBP, IGF 1 receptor interacting protein 1, IIP 1, IIP1, NIP, PDZ domain-containing protein GIPC1, Regulator of G protein signalling 19 interacting protein 1, RGS19 interacting protein 1, RGS19IP1, SEMCAP, SYNECTIIN, Tax interaction protein 2, TIP 2, GIPC1_HUMAN.

    Background: GIPC, for GAIP interacting protein at the C terminus (also designated SEMCAP-1 or synectin), is a PDZ domain containing protein that interacts with RGS-GAIP, a GTPase-activating protein (GAP) for G(a i) subunits. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. PDZ domain-containing proteins are primarily localized to cell-cell junctions in epithelial cells and neurons where they coordinate the assembly of multiprotein complexes. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.

    基因ID

    10755

    UniProt

    O14908

    途径

    Dicarboxylic Acid Transport
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