HMGB3 抗体 (HRP)
Quick Overview for HMGB3 抗体 (HRP) (ABIN6987988)
抗原
See all HMGB3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HMG4/HMGB3:1-100/200
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亚型
- IgG
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应用备注
- IHC-P 1:200-400
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HMGB3 (High Mobility Group Box 3 (HMGB3))
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别名
- HMG4/HMGB3
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背景
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Synonyms: High mobility group (nonhistone chromosomal) protein 4, High mobility group box 3, High mobility group protein 2a, High mobility group protein 4, High mobility group protein B3, High mobility group protein HMG4, HMG 4, HMG-2a, HMG-4, HMG2A, HMGB 3, HMGB3, HMGB3_HUMAN, MGC90319, Non histone chromosomal protein, Nonhistone chromosomal protein HMG4.
Background: HMGB3 belongs to the high mobility group (HMG) protein superfamily. Like HMG1 (MIM 163905) and HMG2 (MIM 163906), HMGB3 contains DNA-binding HMG box domains and is classified into the HMG box subfamily. Members of the HMG box subfamily are thought to play a fundamental role in DNA replication, nucleosome assembly and transcription (Wilke et al., 1997 [PubMed 9370291], Nemeth et al., 2006 [PubMed 16945912]).[supplied by OMIM, Mar 2008] Function : Binds preferentially single-stranded DNA and unwinds double stranded DNA. Similarity : Belongs to the HMGB family. Contains 2 HMG box DNA-binding domains.
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基因ID
- 3149
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UniProt
- O15347
抗原
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