HAND2 抗体 (AA 141-217) (HRP)
Quick Overview for HAND2 抗体 (AA 141-217) (HRP) (ABIN6987860)
抗原
See all HAND2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-217
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HAND2
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亚型
- IgG
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应用备注
- WB 1:300-5000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))
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别名
- HAND2
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背景
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Synonyms: DHAND 2, dHAND, DHAND2, Ehand 2, Ehand2, FLJ16260, HAND 2, Hand2, autonomic nervous system and neural crest derivatives-expressed protein 2, heart, Basic helix loop helix transcription factor HAND2, bHLHa26, Class A basic helix-loop-helix protein 26, Deciduum, Deciduum heart autonomic nervous system and neural crest derivatives expressed protein 2 antibody HAND2_HUMAN, Heart and neural crest derivatives expressed 2, Heart and neural crest derivatives expressed protein 2, heart and neural crest derivatives expressed transcript 2, Heart- and neural crest derivatives-expressed protein 2, Hed, Highly similar to dHAND M musculus, MGC125303, MGC125304, Th 2, Th2, Thing 2, Thing2.
Background: Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).
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基因ID
- 9464
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UniProt
- P61296
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途径
- Tube Formation, Feeding Behaviour
抗原
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