ZIC2 抗体 (AA 131-230) (HRP)
Quick Overview for ZIC2 抗体 (AA 131-230) (HRP) (ABIN6987805)
抗原
See all ZIC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 131-230
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Zic2
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亚型
- IgG
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应用备注
- IHC-P 1:200-400
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ZIC2
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别名
- Zic2
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背景
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Synonyms: HPE 5, HPE5, Odd paired homolog Drosophila, Zic 2, Zic family member 2 (odd paired Drosophila homolog), Zic family member 2, ZIC2, ZIC2_HUMAN, Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2, Zinc finger protein Zic2.
Background: Acts as a transcriptional activator or repressor. Plays important roles in the early stage of organogenesis of the CNS. Activates the transcription of the serotonin transporter SERT in uncrossed ipsilateral retinal ganglion cells (iRGCs) to refine eye-specific projections in primary visual targets. Its transcriptional activity is repressed by MDFIC. Involved in the formation of the ipsilateral retinal projection at the optic chiasm midline. Drives the expression of EPHB1 on ipsilaterally projecting growth cones. Binds to the minimal GLI-consensus sequence 5'-TGGGTGGTC-3'. Associates to the basal SERT promoter region from ventrotemporal retinal segments of retinal embryos.
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基因ID
- 7546
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UniProt
- O95409
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途径
- Tube Formation
抗原
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