ALKBH5 抗体 (AA 1-100) (HRP)
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北京 101111
Quick Overview for ALKBH5 抗体 (AA 1-100) (HRP) (ABIN6987669)
抗原
See all ALKBH5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ALKBH5
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 245-394) antibody
ALKBH5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 302-330) antibodyALKBH5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB38474 unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 1-458) antibodyALKBH5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
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别名
- ALKBH5
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背景
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Synonyms: ABH5, AlkB, alkylation repair homolog 5 (E. coli), AlkB, alkylation repair homolog 5, Alkylated DNA repair protein alkB homolog 5, Alpha ketoglutarate dependent dioxygenase alkB homolog 5, OFOXD, OFOXD1, Oxoglutarate and iron-dependent oxygenase domain containing, Probable alpha ketoglutarate dependent dioxygenase ABH5, RNA demethylase ALKBH5.
Background: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A)RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).
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基因ID
- 54890
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UniProt
- Q6P6C2
抗原
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