Latrophilin 1 抗体 (AA 201-300) (HRP)
Quick Overview for Latrophilin 1 抗体 (AA 201-300) (HRP) (ABIN6987593)
抗原
See all Latrophilin 1 (LPHN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human LPHN1
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亚型
- IgG
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应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Latrophilin 1 (LPHN1)
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别名
- LPHN1
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背景
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Synonyms: Calcium independent alpha latrotoxin receptor 1, Calcium-independent alpha-latrotoxin receptor 1, CIRL-1, CIRL1, CL1, CLIBA, G protein-coupled receptor for alpha-Latrotoxin, KIAA0821, Latrophilin 1, Latrophilin-1, Latrophilin1, LEC2, Lectomedin 2, Lectomedin-2, LPHN 1, LPHN1, LPHN1_HUMAN.
Background: This gene encodes a member of the latrophilin subfamily of G-protein coupled receptors (GPCR). Latrophilins may function in both cell adhesion and signal transduction. In experiments with non-human species, endogenous proteolytic cleavage within a cysteine-rich GPS (G-protein-coupled-receptor proteolysis site) domain resulted in two subunits (a large extracellular N-terminal cell adhesion subunit and a subunit with substantial similarity to the secretin/calcitonin family of GPCRs) being non-covalently bound at the cell membrane. Latrophilin-1 has been shown to recruit the neurotoxin from black widow spider venom, alpha-latrotoxin, to the synapse plasma membrane. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Oct 2008]
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基因ID
- 22859
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UniProt
- O94910
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途径
- Synaptic Membrane, Synaptic Vesicle Exocytosis
抗原
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