电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

SMAD7 抗体 (AA 1-100) (FITC)

SMAD7 适用: 人, 小鼠, 大鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal FITC
产品编号 ABIN6987326
发货至: 中国
  • 抗原 See all SMAD7 抗体
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    抗原表位
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 46
    • 27
    • 25
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 38
    • 7
    • 1
    克隆类型
    • 39
    • 7
    多克隆
    标记
    • 24
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SMAD7 antibody is conjugated to FITC
    应用范围
    • 22
    • 18
    • 13
    • 13
    • 8
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human MADH7
    亚型
    IgG
    Top Product
    Discover our top product SMAD7 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    别名
    MADH7 (SMAD7 产品)
    背景

    Synonyms: hSMAD 7, hSMAD7, MAD (mothers against decapentaplegic Drosophila) homolog 7, MAD, Mad homolog 7, MAD mothers against decapentaplegic homolog 7, MADH 7, MADH 8, MADH8, Mothers Against Decapentaplegic Drosophila Homolog of 7, Mothers against decapentaplegic homolog 7, Mothers against decapentaplegic homolog 8, Mothers against DPP homolog 7, Mothers against DPP homolog 8, SMA- AND MAD-RELATED PROTEIN 7, SMAD 7, SMAD, SMAD family member 7, SMAD, mothers against DPP homolog 7 (Drosophila), SMAD, mothers against DPP homolog 7, Smad7, SMAD7_HUMAN

    Background: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

    基因ID
    4092
    UniProt
    O15105
    途径
    Interferon-gamma Pathway, Cell-Cell Junction Organization
You are here:
客服