COPG1, COPG2 (AA 1-100) 抗体 (Cy7)
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- 抗原
- COPG1, COPG2
- 抗原表位
- AA 1-100
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- Cy7
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Cow
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human COPG2
- 亚型
- IgG
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- COPG1, COPG2
- 别名
- COPG1 + COPG2
- 背景
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Synonyms: 2 COP, Coat protein nonclathrin gamma 2 cop, Coatomer protein complex subunit gamma 2, Coatomer subunit gamma 2, Coatomer subunit gamma-2, COPG 2, Copg2, COPG2_HUMAN, DKFZp761N09121, FLJ11781, Gamma 2 coat protein, Gamma 2 COP, Gamma-2-coat protein, Gamma-2-COP, Coatomer subunit gamma-1, COPG1, Gamma-1-coat protein, Gamma-1-COP, COPG
Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
- 基因ID
- 22820, 26958
- UniProt
- Q9Y678, Q9UBF2
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