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IL12B 抗体 (AA 201-300) (Cy7)

This anti-IL12B antibody is a 兔 多克隆 antibody detecting IL12B in WB, IF (cc) 和 IF (p). Suitable for 人 和 小鼠.
产品编号 ABIN6985800
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for IL12B 抗体 (AA 201-300) (Cy7) (ABIN6985800)

抗原

See all IL12B 抗体
IL12B (Interleukin 12 beta (IL12B))

适用

  • 101
  • 36
  • 12
  • 9
  • 5
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
人, 小鼠

宿主

  • 98
  • 29
  • 11
  • 3
  • 2

克隆类型

  • 86
  • 57
多克隆

标记

  • 90
  • 9
  • 8
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This IL12B antibody is conjugated to Cy7

应用范围

  • 102
  • 53
  • 40
  • 29
  • 29
  • 28
  • 12
  • 12
  • 12
  • 7
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 10
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IL12B (Interleukin 12 beta (IL12B))

    别名

    IL-12 beta

    背景

    Synonyms: CLMF, NKSF, CLMF2, IMD28, IMD29, NKSF2, IL-12B, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, NK cell stimulatory factor chain 2, IL12B

    Background: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

    基因ID

    3593

    UniProt

    P29460

    途径

    JAK/STAT Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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