NCOA1 抗体 (AA 201-300) (Cy7)
Quick Overview for NCOA1 抗体 (AA 201-300) (Cy7) (ABIN6985794)
抗原
See all NCOA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NCOA1
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亚型
- IgG
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anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1222-1441) antibody
NCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (pTyr529) antibodyNCOA1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 1338-1367) antibodyNCOA1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 201-300) antibodyNCOA1 适用: 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 284-393) antibodyNCOA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (N-Term) antibodyNCOA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) (AA 611-660) antibodyNCOA1 适用: 人, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Coactivator 1 (NCOA1) antibodyNCOA1 适用: 人 DB 宿主: 小鼠 Monoclonal 3532C6a unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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别名
- NCOA1
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背景
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Synonyms: Nuclear receptor coactivator 1, NCOA1, NCoA-1, Class E basic helix-loop-helix protein 74, bHLHe74, Protein Hin-2, RIP160, Renal carcinoma antigen NY-REN-52, Steroid receptor coactivator 1, SRC-1, BHLHE74, SRC1
Background: Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4, the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.
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基因ID
- 8648
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UniProt
- Q15788
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
抗原
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