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Metabotropic Glutamate Receptor 5 抗体 (AA 431-530) (Cy5.5)

This anti-Metabotropic Glutamate Receptor 5 antibody is a 兔 多克隆 antibody detecting Metabotropic Glutamate Receptor 5 in WB 和 FACS. Suitable for 大鼠 和 小鼠.
产品编号 ABIN6985301
发货至: 中国

Quick Overview for Metabotropic Glutamate Receptor 5 抗体 (AA 431-530) (Cy5.5) (ABIN6985301)

抗原

See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体
Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

适用

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大鼠, 小鼠

宿主

  • 88
  • 43
  • 2
  • 1
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克隆类型

  • 82
  • 53
多克隆

标记

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This Metabotropic Glutamate Receptor 5 antibody is conjugated to Cy5.5

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 39
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    • 1
    AA 431-530

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Cow,Sheep,Horse,Chicken,Monkey

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human MGLUR5

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

    别名

    MGLUR5

    背景

    Synonyms: MGLUR5B, Glutamate receptor metabotropic 5, GPRC1E, GRM 5, GRM5, Metabotropic glutamate receptor 5, mGlu5, mGluR5, mGluR5a, mGluR5b, Metabotropic glutamate receptor 5 variant F, Metabotropic Glutamate Receptor 5b, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, PPP1R86, GRM5_HUMAN,

    Background: Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.

    基因ID

    2915

    UniProt

    P41594

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
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