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CBX4 抗体 (AA 401-500) (Cy5)

This Cy5-conjugated 兔 多克隆 anti-CBX4 antibody specifically detects CBX4 in WB, IF (cc) 和 IF (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN6984333
发货至: 中国
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Quick Overview for CBX4 抗体 (AA 401-500) (Cy5) (ABIN6984333)

抗原

See all CBX4 抗体
CBX4 (Chromobox Homolog 4 (CBX4))

适用

  • 64
  • 32
  • 7
  • 6
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 61
  • 3

克隆类型

  • 60
  • 4
多克隆

标记

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  • 5
  • 5
  • 5
  • 3
  • 3
  • 1
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This CBX4 antibody is conjugated to Cy5

应用范围

  • 50
  • 32
  • 15
  • 12
  • 12
  • 12
  • 6
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 8
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 401-500

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CBX4

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CBX4 (Chromobox Homolog 4 (CBX4))

    别名

    CBX4

    背景

    Synonyms: PC2, NBP16, E3 SUMO-protein ligase CBX4, Chromobox protein homolog 4, Polycomb 2 homolog, hPc2, CBX4

    Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

    基因ID

    8535

    UniProt

    O00257
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