Metabotropic Glutamate Receptor 5 抗体 (AA 431-530) (Cy3)
Quick Overview for Metabotropic Glutamate Receptor 5 抗体 (AA 431-530) (Cy3) (ABIN6983579)
抗原
See all Metabotropic Glutamate Receptor 5 (GRM5) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 431-530
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Sheep,Horse,Chicken,Monkey
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MGLUR5
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亚型
- IgG
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应用备注
- FCM 1:20-100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))
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别名
- MGLUR5
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背景
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Synonyms: MGLUR5B, Glutamate receptor metabotropic 5, GPRC1E, GRM 5, GRM5, Metabotropic glutamate receptor 5, mGlu5, mGluR5, mGluR5a, mGluR5b, Metabotropic glutamate receptor 5 variant F, Metabotropic Glutamate Receptor 5b, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, PPP1R86, GRM5_HUMAN,
Background: Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.
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基因ID
- 2915
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UniProt
- P41594
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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