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SNF8 抗体 (AA 31-130) (Biotin)

This anti-SNF8 antibody is a 兔 多克隆 antibody detecting SNF8 in ELISA, IHC (p) 和 IHC (fro). Suitable for 大鼠.
产品编号 ABIN6982609
发货至: 中国

Quick Overview for SNF8 抗体 (AA 31-130) (Biotin) (ABIN6982609)

抗原

See all SNF8 抗体
SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This SNF8 antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 31-130

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EAP30

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

    别名

    EAP30

    背景

    Synonyms: Dot3, ELL associated protein of 30 kDa, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22, hVps22, snf8, SNF8 ESCRTII complex subunit homolog (S cerevisiae), SNF8_HUMAN, Vacuolar sorting protein SNF8, Vacuolar-sorting protein SNF8, VPS22.

    Background: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4.

    基因ID

    11267

    UniProt

    Q96H20
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