TERT 抗体 (AA 521-620) (Biotin)
Quick Overview for TERT 抗体 (AA 521-620) (Biotin) (ABIN6982544)
抗原
See all TERT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 521-620
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TERT
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亚型
- IgG
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anti-Telomerase Reverse Transcriptase (TERT) (C-Term) antibody
TERT 适用: 人 WB, ELISA, IHC, IP, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (C-Term) antibodyTERT 适用: 人 WB, ELISA, IHC, IP, IF, FM 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 601-750) antibodyTERT 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 1029-1132) antibodyTERT 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 3H2C12 unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 627-656) antibodyTERT 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 597-611) antibodyVerified TERT 适用: 人 ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) antibodyTERT 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (AA 1268-1341) antibodyTERT 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (pTyr707) antibodyTERT 适用: 人 IF, DB 宿主: 兔 Polyclonal RB16840 unconjugated
anti-Telomerase Reverse Transcriptase (TERT) (pTyr707) antibodyTERT 适用: 人 ELISA, IF, DB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-1000
ELISA 1:500-1000 -
限制
- 仅限研究用
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- TERT (Telomerase Reverse Transcriptase (TERT))
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别名
- TERT
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背景
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Synonyms: EST2, hEST2, TCS1, Telomerase associated protein 2, Telomerase Catalytic Subunit, Telomere Reverse Transcriptase, Telomerase reverse transcriptase, TERT, TP2, TRT, TERT_HUMAN, Telomerase reverse transcriptase, HEST2, Telomerase catalytic subunit, Telomerase-associated protein 2.??
Background: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Telomerase are large DNA-protein complexes with telomerase expression being the subject of recent research due to its link to cell immortalization. Recent evidence has shown that MYC upregulates the catalytic subunit of telomerase, TERT, and that Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified, the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008].
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基因ID
- 7015
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UniProt
- O14746
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途径
- Telomere Maintenance
抗原
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