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DBNL 抗体 (AA 201-300) (AbBy Fluor® 680)

This anti-DBNL antibody is a 兔 多克隆 antibody detecting DBNL in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN6981180
发货至: 中国

Quick Overview for DBNL 抗体 (AA 201-300) (AbBy Fluor® 680) (ABIN6981180)

抗原

See all DBNL 抗体
DBNL (Drebrin-Like (DBNL))

适用

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  • 18
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  • 1
  • 1
小鼠

宿主

  • 30
  • 2
  • 1

克隆类型

  • 31
  • 2
多克隆

标记

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  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This DBNL antibody is conjugated to AbBy Fluor® 680

应用范围

  • 31
  • 13
  • 12
  • 12
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    小鼠

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HIP55

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DBNL (Drebrin-Like (DBNL))

    别名

    HIP55

    背景

    Synonyms: ABP1, Actin-binding protein 1, Cervical mucin associated protein, Cervical mucin-associated protein, Cervical SH3P7, CMAP, Dbnl, DBNL_HUMAN, Drebrin F, drebrin like, Drebrin like protein, Drebrin-F, Drebrin-like protein, HIP 55, HIP-55, HPK1 interacting protein of 55 kDa, HPK1-interacting protein of 55 kDa, SH3 domain containing protein 7, SH3 domain-containing protein 7, SH3P7, Src Homology 3 Domain Containing Protein, src homology 3 domain containing protein HIP

    Background: Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes (By similarity). May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.

    基因ID

    28988

    UniProt

    Q9UJU6

    途径

    TCR Signaling, Regulation of Actin Filament Polymerization
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