CDK7 抗体 (pThr170) (AbBy Fluor® 680)
Quick Overview for CDK7 抗体 (pThr170) (AbBy Fluor® 680) (ABIN6980703)
抗原
See all CDK7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr170
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated Synthesised phosphopeptide derived from human CDK7 around the phosphorylation site of Thr170
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
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别名
- CDK7
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背景
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Synonyms: CDK7 (phospho Thr170), CDK7 (phospho T170), Cyclin H, MAT1, Cyclin Dependent Kinase 7, CAK1, MO15, CDKN7, serine/threonine kinase, STK1, serine/threonine protein kinase 1, MO15 homolog,Xenopus laevis, cdk-activating kinase, Cdk-activating kinase, serine/threonine protein kinase MO15, homolog of Xenopus MO15 Cdk-activating kinase, kinase subunit of CAK, 39 KDa protein kinase, CR4 protein kinase, CRK4, CDK7_HUMAN.
Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
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基因ID
- 1022
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UniProt
- P50613
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途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
抗原
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