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TUBA1B 抗体 (AA 401-451) (AbBy Fluor® 647)

This anti-TUBA1B antibody is a 兔 多克隆 antibody detecting TUBA1B in WB 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6980303
发货至: 中国

Quick Overview for TUBA1B 抗体 (AA 401-451) (AbBy Fluor® 647) (ABIN6980303)

抗原

See all TUBA1B 抗体
TUBA1B (Tubulin, alpha 1B (TUBA1B))

适用

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  • 4
  • 2
  • 1
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 47
  • 14
  • 1

克隆类型

  • 44
  • 18
多克隆

标记

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  • 5
  • 5
  • 4
  • 1
  • 1
  • 1
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  • 1
  • 1
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  • 1
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This TUBA1B antibody is conjugated to AbBy Fluor® 647

应用范围

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  • 12
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  • 4
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  • 2
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  • 1
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 14
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-451

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TUBA1A + TUBA1B

    亚型

    IgG
  • 应用备注

    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TUBA1B (Tubulin, alpha 1B (TUBA1B))

    别名

    TUBA1A + TUBA1B

    背景

    Synonyms: TUBA1A + TUBA1B, Tubulin, Alpha 1b, Tubulin Alpha-Ubiquitous Chain, Alpha-Tubulin Ubiquitous, Tubulin K-Alpha-1, Tubulin, Alpha, Ubiquitous, Tubulin Alpha-1B Chain, Alpha Tubulin, Ubiquitous, K-ALPHA-1, Tubulin Alpha, TBA1B_HUMAN, Tubulin, Alpha 1a, TUBA3, Tubulin Alpha-3 Chain, Tubulin B-Alpha-1, LIS3, Tubulin, Alpha, Brain-Specific, Tubulin Alpha-1A Chain, Alpha-Tubulin 3, Brain-Specific, Hum-A-Tub1, Hum-A-Tub2, B-ALPHA-1, TBA1A_HUMAN, ,____alpha

    Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

    基因ID

    7846

    UniProt

    Q71U36

    途径

    Microtubule Dynamics, M Phase
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